Phospho-IkB alpha (Ser32/S36) Polyclonal Antibody | E-AB-20911

Phospho-IkB alpha (Ser32/S36) Polyclonal Antibody | E-AB-20911 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: I kappa B alpha, I-kappa-B-alpha, IkappaBalpha, IkB-alpha, IKBA, IKBA, IKBalpha, MAD 3, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappa-B inhibitor alpha, NFKBI, NFKBIA, Nuclear factor of kappa light chain gene enhancer in B cells, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha

Application: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Background: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human IκB-α around the phosphorylation site of Ser32/36

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 36 kDa

Molecular Weight(Observed): 34 kDa