Phospho-IRS1 (Ser636) Polyclonal Antibody | E-AB-20908

Phospho-IRS1 (Ser636) Polyclonal Antibody | E-AB-20908 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: HIRS 1, HIRS1, Insulin receptor substrate 1, IRS 1, IRS-1, IRS1, IRS1, OTTHUMP00000164234

Application: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Tags and Cell Markers

Background: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser636

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 132 kDa

Molecular Weight(Observed): 150 kDa