Phospho-Jak3(Y980/981) Polyclonal Antibody | E-AB-68173

Phospho-Jak3(Y980/981) Polyclonal Antibody | E-AB-68173 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: JAK3, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK

Application: WB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A synthetic phosphorylated peptide around Y980 of human Jak3 (NP_000206.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 68 kDa/121 kDa/125 kDa

Molecular Weight(Observed): 110 kDa