Phospho-MAP3K7 (Thr187) Polyclonal Antibody | E-AB-21065

Phospho-MAP3K7 (Thr187) Polyclonal Antibody | E-AB-21065 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: M3K7, MAP3K 7, Map3k7, MEKK7, Mitogen activated protein kinase kinase kinase 7, Mitogen-activated protein kinase kinase kinase 7, TAK1, TGF beta activated kinase 1, TGF-beta-activated kinase 1, TGF1a, Transforming growth factor beta activated kinase 1, Transforming growth factor-beta-activated kinase 1

Application: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Immunology, Signal Transduction

Background: Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human Tak1 around the phosphorylation site of Thr187

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 67 kDa

Molecular Weight(Observed): 60 kDa