Phospho-MYC (T58) Antibody [APR05172G]

Phospho-MYC (T58) Antibody [APR05172G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.

Cellular Localisation: Nucleus, nucleoplasm. Nucleus, nucleolus

Molecular Weight: 48804

Clone: Polyclonal

Gene Name: MYC

Gene ID: 4609

Function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029) . Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029) . Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029) . Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity) . Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: DB, WB

Dilution: DB--1:500 WB--1:1000

Synonyms: Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39