phospho-NeuroD1 (Ser274) Polyclonal Antibody | BS65833

phospho-NeuroD1 (Ser274) Polyclonal Antibody | BS65833 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Pig,Cow,Sheep,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]

Storage & Stability: Store at 4°C short term. Aliquot and store at -6°C long term. Avoid freeze-thaw cycles.

Specificity: phospho-NeuroD1 (Ser274) Polyclonal Antibody detects endogenous levels of NeuroD1 protein only when phosphorylated at Y274.

Molecular Weight: ~40 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: NeuroD1 (phospho S274) ; p-NeuroD1 (phospho S274) ; atonal; basic helix loop helix transcription factor; BETA 2; Beta cell E box transactivator 2; BETA2; BHF 1; BHF1; bHLHa3; class A basic helix loop helix protein 3; Class A basic helix-loop-helix protein 3; MODY 6; MODY6; NDF1_HUMAN; NEUROD; NeuroD1; Neurogenic differentiation 1; Neurogenic differentiation factor 1; neurogenic helix loop helix protein NEUROD; NIDDM

Immunogen: KLH conjugated Synthesised acetylpeptide derived from human NeuroD1 around the acetylation site of Ser274:PL (p-S) PP

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: affinity purified by Protein A

Pathway: