phospho-Nrf2 (Ser40) monoclonal Antibody | BS65507

phospho-Nrf2 (Ser40) monoclonal Antibody | BS65507 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: IHC-P

Application Range: IHC-P=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor which regulates the expression of many detoxification and antioxidant enzymes. Nrf2 can potentially play a significant role in adaptive responses to oxidative stress. Nrf2 belongs to the Cap N Collar (CNC-bZIP) subfamily of basic /leucine zipper (bZIP) transcription factors.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Phospho-Nrf2 (Ser40) monoclonal Antibody detects endogenous levels of Nrf2 protein only when phosphorylated at Ser40.

Molecular Weight: ~100 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Nrf2 (phospho S40) ; p-Nrf2 (phospho S40) ; Nuclear factor-E2 related factor2; HEBP1; NF E2 related factor 2; NFE2 related factor 2; NFE2L2; Nrf 2; Nuclear factor erythroid 2 related factor 2; Nuclear factor erythroid derived 2 like 2; NF2L2_HUMAN.

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Nrf2 around the phosphorylation site of Ser40:DF (p-S) QR

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: affinity purified by Protein A

Pathway: