Phospho TGFBR2 (Ser225) Antibody | A1975

The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

A1975 | Phospho TGFBR2 (Ser225) Antibody DataSheet

Antibody Target: Phospho TGFBR2 (Ser225)

Target Alternative Name: TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II

Tag Line: Affinity purified rabbit polyclonal antibody to detect phosphorylation of TGFBR2 at Ser225 in human, mouse, rat, porcine, rabbit samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Porcine, Rat, Rabbit, Mouse, Human

Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the center region of human TGFBR2

Accession #: P37173

Gene ID: 7048

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application: Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:1000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False