Phospho-YAP1(S127) Polyclonal Antibody | E-AB-68161

Phospho-YAP1(S127) Polyclonal Antibody | E-AB-68161 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: COB1, YAP, YAP2, YAP65, YKI, YAP1

Application: WB, IF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000 IF 1:20-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 36 kDa/48 kDa/49 kDa/50 kDa/52 kDa/53 kDa/54 kDa

Molecular Weight(Observed): 60 kDa/68 kDa