PHOX2B Antibody (Center) [APR30767G]

PHOX2B Antibody (Center) [APR30767G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This PHOX2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-130 amino acids from the Central region of human PHOX2B.

Cellular Localisation: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.

Molecular Weight: 31621

Clone: Polyclonal

Gene Name: PHOX2B

Gene ID: 8929

Function: Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta- hydrolase and c-fos promoters, and of several enhancers including cAMP- response element and serum-response element.

Summary: Tissue Location: Expressed in neuroblastoma, brain and adrenal gland

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IF, WB

Dilution: IF--1:10~50 WB--1:1000

Synonyms: Paired mesoderm homeobox protein 2B, Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B, PHOX2B, PMX2B