PHOX2B Antibody| F41391-0.08ML/F41391-0.4ML

PHOX2B Antibody| F41391-0.08ML/F41391-0.4ML | Gentaur UK, US & Europe Distribution

Background: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq].

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Mouse

Predicted Spacies Reactivity: Human, Rat

Application: IF, WB, ELISA

Application Details: Immunofluorescence: 1:10-1:50, Western blot: 1:1000

Application Note: Titration of the PHOX2B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This PHOX2B antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 104-130 from the human protein was used as the immunogen for this PHOX2B antibody.

Storage: Aliquot the PHOX2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A