PIAS2 Polyclonal Antibody | E-AB-13005

PIAS2 Polyclonal Antibody | E-AB-13005 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Androgen receptor interacting protein 3, Androgen receptor-interacting protein 3, ARIP3, DAB2 interacting protein, DAB2-interacting protein, DIP, E3 SUMO protein ligase PIAS2, E3 SUMO-protein ligase PIAS2, MIZ, Miz1, Msx interacting zinc finger protein, Msx-interacting zinc finger protein, PIAS NY protein, PIAS-NY protein, PIAS2, PIAS2, PIASX, PIASX-ALPHA, PIASX-BETA, Protein inhibitor of activated STAT x, Protein inhibitor of activated STAT, 2, Protein inhibitor of activated STAT2, SIZ2, Zinc finger, MIZ-type containing 4, ZMIZ4

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology, Epigenetics and Nuclear Signaling

Background: This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human PIAS2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A