400

PIK3R1 + PIK3R3 Antibody (pTyr467/199)- Biotin

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SKU:
400-SPC-1416D-BI-GEN
Availability:
IN STOCK
$2,243.50

Description

Rabbit Anti-Human PIK3R1 + PIK3R3 (pTyr467/199) Polyclonal

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Additional Information

Size:
100 µl
Target:
PIK3R1 + PIK3R3 (pTyr467/199)
Conjugate:
Biotin
Research Area:
Cell Signaling | Lipid Signaling | Lipid Kinases | Cancer | Immunology | Innate Immunity | TLR Signaling
Alternative Name:
PIK3R1 + PIK3R3 Antibody, PI3-kinase p85- alpha/ gamma Antibody, Phosphatidylinositol 3 kinase catalytic alpha polypeptide Antibody, PI3K Antibody, PIK3R1 Antibody, PI3K alpha Antibody, PtdIns 3 kinase regulatory subunit alpha Antibody, Phosphatidyli
Category:
Antibodies
Product Type:
Polyclonal Antibody
Immunogen:
Synthetic phospho-peptide from human PIK3R1 + PIK3R3 proteins around the phosphorylation site of PI3-kinase p85- alpha at tyrosine 467 (pTyr467) and PI3-kinase p85- gamma at tyrosine 199 (pTyr199).
Immunogen Species:
Human
Applications:
WB, ICC/IF
Host:
Rabbit
Isotype:
IgG
Species Reactivity:
Human, Mouse, Rat
Antibody Dilution:
WB (1:250-1:1000); ICC/IF (1:50-1:250); optimal dilutions for assays should be determined by the user.
Purification:
Peptide Affinity Purified
Storage Buffer:
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Concentration:
N/A
Specificity:
Detects endogenous levels of PI3-kinase p85- alpha only when phosphorylated at tyrosine 467 (pTyr467) and PI3-kinase p85- gamma only when phosphorylated at tyrosine 199 (pTyr199). Detects a band at ~55 kDa.
Storage:
-20ºC
Shipping:
Blue Ice or 4ºC
Certificate of Analysis:
N/A
Cellular Localization:
Cytosol, Endoplasmic Reticulum, Perinuclear Endoplasmic Reticulum Membrane, Nucleus, Plasma Membrane, Cell-Cell Junction, Cis-Golgi Network, Cytoplasm, Membrane, Phosphatidylinositol 3-Kinase Complex, Phosphatidylinositol 3-Kinase Complex Class Ia, P
Tissue Specificity:
Isoform 2 is expressed in skeletal muscle and brain, and at lower levels in kidney and cardiac muscle. Isoform 2 and isoform 4 are present in skeletal muscle (at protein level). Highest levels in brain and testis. Lower levels in adipose tissue, kidn
Accession Number:
NP_001229395.1/NP_001107644.1
Gene ID:
5295/8503
Swiss-Prot:
P27986/Q92569
Field of Use:
For in vitro research use only.
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