PIM1 Polyclonal Antibody | E-AB-10915

PIM1 Polyclonal Antibody | E-AB-10915 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Oncogene PIM 1, Oncogene PIM1, PIM 1, pim 1 kinase 44 kDa isoform, Pim 1 kinase, pim 1 oncogene (proviral integration site 1), Pim 1 oncogene, PIM, PIM1, pim1 kinase 44 kDa isoform, PIM1, Pim2, PIM3, Proto oncogene serine/threonine protein kinase Pim 1, Proto-oncogene serine/threonine-protein kinase Pim-1, Proviral integration site 1, Proviral integration site 2

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells

Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human PIM1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A