Pixantrone maleate | 1958

An analog of Mitoxantrone (Cat. No. 1885-50, 250) that displays antitumor properties with fewer toxic effects on cardiac tissue. Acts as a topoisomerase II poison and intercalating agent.

Pixantrone maleate is an analog of Mitoxantrone (Cat. No. 1885-50, 250) that displays antitumor properties with fewer toxic effects on cardiac tissue. Acts as a topoisomerase II poison and intercalating agent.

1958 | Pixantrone maleate DataSheet

Alternate Name/Synonyms: Benz(G)isoquinoline-5,10-dione, 6,9-bis((2-aminoethyl)amino)-, (2Z)-2-butenedioate (1:2); BBR-2778

Appearance: Off-white solid

Formulation: N/A

CAS Number: 144675-97-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₉N₅O₂.C₈H₈O₈

Molecular Weight: 557.52

Cell-Permeable?: No

Purity: ≥98% by HPLC

Solubilities: DMSO or water

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A topoisomerase II inhibitor

MDL Number: MFCD00920108

PubChem CID: 9937618

SMILES: C1=CC(=C2C(=C1NCCN)C(=O)C3=C(C2=O)C=NC=C3)NCCN.C(=CC(=O)O)C(=O)O.C(=CC(= O)O)C(=O)O

InChi: InChI=1S/C17H19N5O2.2C4H4O4/c18-4-7-21-12-1-2-13(22-8-5-19)15-14(12)16 (23)10-3-6-20-9-11(10)17(15)24;2*5-3(6)1-2-4(7)8/h1-3,6,9,21-22H,4-5, 7-8,18-19H2;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

InChi Key: SVAGFBGXEWPNJC-SPIKMXEPSA-N