Description
PKCδ polyclonal Antibody | BS91084 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IHC
Application Range: WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200
Background: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms (δ, ε, ζ, η, θ, λ/ι, μ and ν) . Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: PKCδ polyclonal Antibody detects endogenous levels of PKCδ protein.
Molecular Weight: 78 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: PRKCD, CVID9, D14Ertd420e, Kinase PKC delta, KPCD, KPCD, MAY 1, MAY1, MGC49908, nPKC delta, nPKC-delta, PCKd, PKC d, PKC delta, PKCD, PKCdelta, PRKC D, PRKC delta, Prkcd, Protein Kinase C delta, Protein kinase C delta type, Protein kinase C delta VIII, Protein Kinase Cdelta, Tyrosine protein kinase PRKCD,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: