PKCμ polyclonal Antibody | BS91086

PKCμ polyclonal Antibody | BS91086 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB:1:500-1:2,000

Background: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: PKCμ polyclonal Antibody detects endogenous levels of PKCμ protein.

Molecular Weight: 102 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PRKD1, PKD, PKD1, PRKCM, KPCD1, nPKC D1, nPKC mu, nPKC-D1, nPKC-mu, nPKCD1, nPKCmu, PKC, PKC MU, PKCM, PKCmu, PKD 1, PKD, PKD1, PRKCM, PRKD 1, Prkd1, Protein kinase C mu, Protein kinase C mu type, Protein kinase D, Protein kinase D1, Serine/threonine protein kinase D1, Serine/threonine-protein kinase D1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: