PKC zeta Polyclonal Antibody | E-AB-32609

PKC zeta Polyclonal Antibody | E-AB-32609 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 14-3-3-zetaisoform, AI098070, aPKCzeta, C80388, EC 2.7.11.13, KPCZ, nPKC zeta, nPKC-zeta, OTTHUMP00000001368, OTTHUMP00000044160, PKC 2, PKC ZETA, PKC2, Pkcz, PKCZETA, PKM-zeta, included, PRKCZ, Protein kinase C zeta, Protein kinase C zeta form, Protein kinase C zeta type, r14-3-3, R74924, zetaPKC

Application: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human PKC ζ around the non-phosphorylation site of Thr560.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 68 kDa

Molecular Weight(Observed): 80 kDa