PKD2 (A872) polyclonal Antibody | BS1584

PKD2 (A872) polyclonal Antibody | BS1584 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: PKD2 (protein kinase D2), also known as PRKD2 or HSPC187, is a widely expressed protein belonging to the protein kinase D (PKD) family of serine/threonine kinases. In mammals, there are three members of the PKD family, namely PKC µ, PKD2 and PKC n, and each contain a homologous catalytic domain but differ in their tissue expression and subcellular localization. PKD family members are activated by G-protein-coupled receptors (GPCRs) and are known to participate in biological processes such as proliferation, apoptosis, migration, signal transduction and vesicle shedding. Shuttling between the nucleus and the cytoplasm, PKD2 contains one PH domain, one protein kinase domain and two phorbol-ester/DAG-type zinc fingers, and functions as a calcium-independent, phospholipid-dependent protein kinase.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PKD2 (A872) polyclonal Antibody detects endogenous levels of PKD2 protein.

Molecular Weight: ~ 96 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Serine/threonine-protein kinase D2; nPKC-D2; PRKD2; PKD2; HSPC187;

Immunogen: Synthetic peptide, corresponding to amino acids 840-890 of Human PKD2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Contribution of Soluble Factors to EMT,