PKP4 Antibody (C-term) [AMM07218G]

PKP4 Antibody (C-term) [AMM07218G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This PKP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1040-1068 amino acids from the C-terminal region of human PKP4.

Cellular Localisation: Cell junction, desmosome. Cytoplasm, cytoskeleton, spindle. Midbody Cell membrane; Peripheral membrane protein. Note=Associated with the pericentrosomal region in interphase and with spindle poles during mitosis. In anaphase, during chromosome segregation, is recruited to the central microtubule bundle, focussed at the spindle midzone and ultimately localizes to the midbody at cytokinesis. Constituent of the midbody cytoskeletal matrix. Colocalized with desmoplakin at desmosomal junctional plaques in cultured epithelial cells

Molecular Weight: 131868

Clone: Polyclonal

Gene Name: PKP4

Gene ID: 8502

Function: Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100

Synonyms: Plakophilin-4, p0071, PKP4