PLpro inhibitor | B2757

PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) (IC50 = 2.6 µM). PLpro inhibitor inhibits SARS-CoV-2 PLpro with an IC50 of 5.0 µM and an EC50 of 21.0 µM.

PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) (IC50 = 2.6 µM). PLpro inhibitor inhibits SARS-CoV-2 PLpro with an IC50 of 5.0 µM and an EC50 of 21.0 µM.

B2757 | PLpro inhibitor DataSheet

Alternate Name/Synonyms: KOM70144,(R)-5-acetamido-2-methyl-N-(1-(naphthalen-1-yl)ethyl)benzamide

Appearance: Crystalline solid

Formulation:

CAS Number: 1093070-14-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₂N₂O₂

Molecular Weight: 346.43

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A papain-like protease (PLpro) inhibitor

MDL Number:

PubChem CID: 312811351

SMILES: O=C(C1=CC(NC(C)=O)=CC=C1C)N[C@H](C)C2=C(C=CC=C3)C3=CC=C2

InChi: InChI=1S/C22H22N2O2/c1-14-11-12-18(24-16(3)25)13-21(14)22(26)23-15(2)19-10-6-8-17-7-4-5-9-20(17)19/h4-13,15H,1-3H3,(H,23,26)(H,24,25)/t15-/m1/s1

InChi Key: KGPYBLOBHQLIET-OAHLLOKOSA-N