PLXNB1 Antibody (C-term) [APR12903G]

PLXNB1 Antibody (C-term) [APR12903G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PLXNB1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1715-1749 amino acids from the C-terminal region of human PLXNB1.

Cellular Localisation: [Isoform 1]: Cell membrane; Single-pass type I membrane protein [Isoform 3]: Secreted

Molecular Weight: 232298

Clone: Polyclonal

Gene Name: PLXNB1

Gene ID: 5364

Function: Receptor for SEMA4D (PubMed:19843518, PubMed:20877282, PubMed:21912513) . Plays a role in GABAergic synapse development (By similarity) . Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development (By similarity) . Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12196628, PubMed:15210733) . Plays a role in axon guidance, invasive growth and cell migration (PubMed:12198496) .

Summary: Tissue Location: Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Plexin-B1, Semaphorin receptor SEP, PLXNB1, KIAA0407, PLXN5, SEP