PM20D1 Antibody (N-Term) [APR33303G]

PM20D1 Antibody (N-Term) [APR33303G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PM20D1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 125-159 amino acids from the human region of human PM20D1.

Cellular Localisation: Secreted {ECO:0000250|UniProtKB:Q8C165}.

Molecular Weight: 55741

Clone: Polyclonal

Gene Name: PM20D1 (HGNC:26518)

Gene ID: 148811

Function: Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase (PubMed:27374330) . It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction (PubMed:27374330) . Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1- independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure. PM20D1 circulates in tight association with both low- and high-density (LDL and HDL, respectively) lipoprotein particles (By similarity) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Probable carboxypeptidase PM20D1, 3417-, Peptidase M20 domain-containing protein 1, PM20D1