PMSF | 1548

An irreversible inhibitor of serine proteases (such as thrombin, trypsin and chymotrypsin) and mammalian acetylcholinesterase. It causes sulfonylation of the active-site serine residues. Inhibits cysteine proteases like papain (reversible by DTT treatment). Also inhibits internucleosomal DNA fragmentation in immature thymocytes.

PMSF is a an irreversible inhibitor of serine proteases (such as thrombin, trypsin and chymotrypsin) and mammalian acetylcholinesterase. It causes sulfonylation of the active-site serine residues. Inhibits cysteine proteases like papain (reversible by DTT treatment). Also inhibits internucleosomal DNA fragmentation in immature thymocytes.

1548 | PMSF DataSheet

Alternate Name/Synonyms: α-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, Phenylmethylsulfonyl fluoride

Appearance: White solid

Formulation: N/A

CAS Number: 329-98-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₇H₇FO₂S

Molecular Weight: 174.2

Cell-Permeable?: No

Purity: ≥99%

Solubilities: EtOH (10%)

Handling: Protect from moisture

Country of Origin: USA

Tag Line: A serine protease inhibitor

MDL Number: MFCD00007424

PubChem CID: 4784

SMILES: C1=CC=C(C=C1)CS(=O)(=O)F

InChi: InChI=1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2

InChi Key: YBYRMVIVWMBXKQ-UHFFFAOYSA-N