PNMT Antibody | 14-158

PNMT Antibody | 14-158 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: A synthetic peptide of human PNMT

Research Area: Cancer, Neuroscience

Tested Application: WB

Application: WB: 1:500 - 1:1000

Specificiy: N/A

Positive Control 1: SW620

Positive Control 2: HT-29

Positive Control 3: MCF7

Positive Control 4: 293T

Positive Control 5: U-87MG

Positive Control 6: N/A

Molecular Weight: Observed: 35kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, pH7.3.

Concentration: N/A

Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.

Alternate Name: PENTase, PNMT, phenylethanolamine N-methyltransferase, noradrenaline N-methyltransferase, phenylethanolamine N-methylase

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline) . The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.