PNPLA6 polyclonal Antibody | BS61695

PNPLA6 polyclonal Antibody | BS61695 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Neuropathy target esterase (NTE) is a member of a newly discovered protein family, with a domain conserved through evolution. It is an integral membrane protein present in all neurons and in some non-neural cell types of vertebrates. NTE is important in neural development and has the capacity to hydrolyse esters. It is important in the cell-signalling pathway controlling interactions between neurons and accessory glial cells in nervous system development. NTE can be modified by organophosphates, which can cause neuropathy (characterized by axonal degeneration) in humans. NTE loss can lead to prominent neuronal pathology in the thalamus amd hippocampus and can also lead to defects in the cerebellum.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PNPLA6 polyclonal Antibody detects endogenous levels of PNPLA6 protein.

Molecular Weight: ~ 150 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6; PNPLA6; NTE

Immunogen: Synthetic peptide, corresponding Human PNPLA6.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: