Podophyllotoxin | 2767

Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Displays anticancer properties. Also antiviral and antihelminthic.

Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Displays anticancer properties. Also antiviral and antihelminthic.

2767 | Podophyllotoxin DataSheet

Alternate Name/Synonyms: (10R,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.03,7.011,15]hexadeca-1,3(7),8-trien-12-one ; (-)-Podophyllotoxin; Condyline; Condylox; NSC 24818; Podofilox;PPT

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 518-28-5, 4354-76-1

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₂O₈

Molecular Weight: 414.41

Cell-Permeable?: Y

Purity: ≥98% by HPLC

Solubilities: EtOH (>35 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A potent inhibitor of microtubule assembly and DNA topoisomerase II

MDL Number: MFCD00075290

PubChem CID: 10607

SMILES: COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O

InChi: InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1

InChi Key: YJGVMLPVUAXIQN-XVVDYKMHSA-N