POLD2 Antibody | 22-502

POLD2 Antibody | 22-502 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-360 of human POLD2 (NP_006221.2) .

Research Area: Other

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: HL-60

Positive Control 3: HepG2

Positive Control 4: BT-474

Positive Control 5: NCI-H460

Positive Control 6: Mouse testis

Molecular Weight: Observed: 51kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: DNA polymerase delta subunit 2, DAN polymerase delta 2, accessory subunit, DNA polymerase delta subunit p5Pol delta B subunit (p50) , polymerase (DNA directed) , delta 2, accessory subunit, polymerase (DNA directed) , delta 2, regulatory subunit 50kDa, polymerase (DNA) delta 2, accessory subunit

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA) . Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.