POLR2B Antibody | 19-948

POLR2B Antibody | 19-948 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human POLR2B (NP_000929.1) .

Research Area: Neuroscience

Tested Application: WB, IHC

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: SH-SY5Y

Positive Control 2: A375

Positive Control 3: HepG2

Positive Control 4: BT-474

Positive Control 5: Mouse brain

Positive Control 6: Mouse spleen

Molecular Weight: Observed: 134kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: POLR2B, RPB2, POL2RB, hsRPB2, hRPB140

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes the second largest subunit of RNA polymerase II (Pol II) , a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants.