POMK Polyclonal Antibody | E-AB-65350

POMK Polyclonal Antibody | E-AB-65350 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: POMK, MDDGA12, MDDGC12, SGK196

Application: WB

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction

Background: This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human POMK (NP_115613.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:200-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 40 kDa

Molecular Weight(Observed): 45 kDa