Description
POSTN Polyclonal Antibody | E-AB-40278 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Fasciclin-I like, MGC119510, MGC119511, OSF 2, OSF2, Osteoblast specific factor 2 (fasciclin I like), Osteoblast specific factor 2, PDLPOSTN, Periodontal ligament specific periostin, Periostin, Periostin isoform thy2, PN, POSTN,
Application: IHC, IF
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cardiovascular, Signal Transduction, Tags and Cell Markers
Background: Periostin (POSTN, PN), originally named as osteoblast-specific factor 2 (OSF-2), is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues, and has a role in bone, tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types, includidng lung, ovary, breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour, and it is required to allow cancer stem cell maintenance.
Concentration: 0.79 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human Periostin protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method: Antigen Affinity Purification
Dilution: IHC 1:100-1:200 IF 1:100-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A