PP1A / PPP1CA (N-terminus) monoclonal Antibody | MB0084

PP1A / PPP1CA (N-terminus) monoclonal Antibody | MB0084 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Application: WB IHC ICC

Application Range: WB: 1:1000 ICC: 1:200~400 IHC: 1:500

Background: Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca (2+) /calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role. in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of PP1A (N-terminus) and does not cross-react with related proteins

Molecular Weight: Predicted band size:38KDa Observed band size:38KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; PP-1A; PPP1CA; PPP1A

Immunogen: Synthetic peptide, corresponding to the N-terminus of Human PP1A / PPP1CA.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Nuclear Receptor Signaling,Epigenetic Writers and Erasers of Histone H3,