PP2 | 1767

An inhibitor of the Src family of kinases. Inhibits Src and Lck kinase with IC₅₀ values of 36 nM and 31 nM respectively. Also shown to inhibit RIP2( IC₅₀ = 19 nM) and CK1δ (IC₅₀ = 41 nM).

PP2 is an inhibitor of the Src family of kinases. Inhibits Src and Lck kinase with IC₅₀ values of 36 nM and 31 nM respectively. Also shown to inhibit RIP2( IC₅₀ = 19 nM) and CK1δ (IC₅₀ = 41 nM).

1767 | PP2 DataSheet

Alternate Name/Synonyms: 1-tert-Butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Appearance: Cream solid

Formulation: N/A

CAS Number: 172889-27-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₆ClN₅

Molecular Weight: 301.78

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (25 mM) and EtOH (10 mM)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An inhibitor of the Src family of kinases

MDL Number: MFCD01568210

PubChem CID: 4878

SMILES: CC(C)(C)N1C2=C(C(=N1)C3=CC=C(C=C3)Cl)C(=NC=N2)N

InChi: InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19)

InChi Key: PBBRWFOVCUAONR-UHFFFAOYSA-N