PPA1 polyclonal Antibody | BS6699

PPA1 polyclonal Antibody | BS6699 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:2000

Background: PPA1 (Pyrophosphate phospho-hydrolase 1), also known as IOPPP (inorganic pyrophosphatase), PP1, PP or PPase, belongs to the PPase family of inorganic pyrophosphatases. Inorganic pyrophosphatases catalyze the intracellular conversion of pyrophosphate to inorganic phosphate, a key reaction for phosphate metabolism in cells. PPA1 is a ubiquitously expressed protein that localizes to the cytoplasm and is required for cell growth. It exists as a homodimer exhibiting magnesium dependent activity. The binding of two magnesium ions is required to stimulate PPA1 activity; however, both subunits in the homodimer are capable of binding four magnesium ions. The additional ions are useful in forming complexes with substrates and products. In addition, the activity of PPA1 can be inhibited by calcium.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PPA1 polyclonal Antibody detects endogenous levels of PPA1 protein.

Molecular Weight: ~ 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Inorganic pyrophosphatase; IOPPP; IPYR; PPA1; PPase; Pyp; Pyrophosphate phospho hydrolase; Pyrophosphate phospho-hydrolase;

Immunogen: Recombinant full length Human PPA1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: