PPARG, Human Recombinant | P1120

Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferators activated receptors (PPARs). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids.

P1120 | PPARG Human Recombinant DataSheet

Biomolecule/Target: PPARG

Synonyms: Peroxisome proliferator-activated receptor gamma, PPAR-gamma, PPARG, NR1C3, PPARG1, PPARG2

Alternates names: Peroxisome proliferator-activated receptor gamma, PPAR-gamma, PPARG, NR1C3, PPARG1, PPARG2

Taglines: Recombinant Human PPAR can be used in the inhibition assays, western blotting, ELISA, and numerous such applications

NCBI Gene ID #: 8600

NCBI Gene Symbol: OPG

Gene Source: Human

Accession #: O14788

Recombinant: Yes

Source: E.coli

Purity by SDS-PAGEs: 98%

Assay: N/A

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to neutralize the stimulation of U937 cells treated with 10 ng/ml of sRANKL.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 80 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: In 50 mM Tris-HCl and 10 mM L-glutathione (reduced).

Reconstitution Instructions: Reconstitute in 5 mM Tris, pH 7.5 to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A