PPBP Polyclonal Antibody | E-AB-19288

PPBP Polyclonal Antibody | E-AB-19288 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: B TG1, Beta TG, Beta thromboglobulin, Beta-TG, C-X-C motif chemokine 7, Chemokine (C X C motif) ligand 7, Connective tissue activating peptide III, CTAP 3, CTAP III, CTAP-III, CTAP-III(1-81), CTAP3, CTAPIII, CXC chemokine ligand 7, CXCL 7, CXCL7, CXCL7, LA PF 4, LA-PF4, LDGF, Leukocyte derived growth factor, Leukocyte-derived growth factor, Low-affinity platelet factor IV, Macrophage-derived growth factor, MDGF, NAP 2, NAP-2, NAP-2(1-63), NAP-2(1-66), NAP-2(73), NAP-2(74), Neutrophil activating peptide 2, Neutrophil-activating peptide 2(1-63), PBP, Platelet basic protein, PPBP, Pro platelet basic protein (chemokine (C-X-C motif) ligand 7), Pro platelet basic protein, SCYB7, Small inducible cytokine subfamily B member 7, Small-inducible cytokine B7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, Thrombocidin 1, Thrombocidin 2, Thromboglobulin, beta-1

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cardiovascular, Immunology, Signal Transduction

Background: PPBP (Pro-Platelet Basic Protein) is a Protein Coding gene. Diseases associated with PPBP include Erythromelalgia and Colloid Adenoma. Among its related pathways are GPCR Pathway and Peptide ligand-binding receptors. GO annotations related to this gene include growth factor activity and glucose transmembrane transporter activity. An important paralog of this gene is CXCL1. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.

Concentration: 0.8 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human PPBP

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:25-1:100, ELISA 1:2000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 14 kDa

Molecular Weight(Observed): Refer to figures