PPFIA3 Antibody | 7561

PPFIA3 Antibody | 7561 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: PPFIA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PPFIA3.
The immunogen is located within amino acids 1100 - 1150 of PPFIA3.

Research Area: Neuroscience

Tested Application: E, WB

Application: PPFIA3 antibody can be used for detection of PPFIA3 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: PPFIA3 antibody is human, mouse, and rat reactive.

Positive Control 1: Cat. No. 1210 - HEK293 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 131 kDa
Observed: 131 kDa

Validation: N/A

Isoform: N/A

Purification: PPFIA3 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PPFIA3 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: PPFIA3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: PPFIA3 Antibody: LPNA3, KIAA0654, Liprin-alpha-3, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3, PTPRF-interacting protein alpha-3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The PPFIA3 protein is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family, a family of transmembrane protein tyrosine phosphatases known to be important for axon guidance and mammary gland development (1) . Similar to the other liprin family members, PPFIA3 can interact with ERC2, a member of the ELKS-Rab6-interacting protein-CAST family of proteins at the presynaptic termini, suggesting that these proteins may play a role in the molecular organization of presynaptic zones (2) .