Description
PPIH Antibody | XW-7879 | Gentaur UK, US & Europe Distribution
Host: Chicken
Reactivity: Human, Mouse
Homology: N/A
Immunogen: 1-177
Research Area: Other
Tested Application: WB
Application: Peptidyl-prolyl cis-trans isomerase H antibody can be used for the detection of Peptidyl-prolyl cis-trans isomerase H by Western Blot.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 19.2 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: PPIH antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: CYP20, CYPH, Peptidyl-prolyl cis-trans isomerase H, Rotamase H, PPIase H, CYP-20, USA-CYP, SnuCyp-20, Peptidylprolyl cistrans isomerase H, U-snRNP-associated cyclophilin SnuCyp-20, Small nuclear ribonucleoprotein particle-specific cyclophilin H, CypH
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FUNCTION: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex. May act as a chaperone.
CATALYTIC ACTIVITY: Peptidylproline (omega=180) = peptidylproline (omega=0) .
SUBUNIT: Interacts directly with PRPF4. Part of a heteromeric complex containing PPIH, PRPF3 and PRPF4 that is stable in the absence of RNA. This complex interacts with the U4/U5/U6 tri-snRNP complex. Heterodimer with PRPF18.