PPM1B monoclonal Antibody | MB64591

PPM1B monoclonal Antibody | MB64591 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:2000, IHC 1:150

Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: protein phosphatase, Mg2+/Mn2+ dependent 1B

Molecular Weight: 52.5 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX

Immunogen: Full length human recombinant protein of human PPM1B (NP_002697) produced in HEK293 cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A