PPM1F Polyclonal Antibody | E-AB-16729

PPM1F Polyclonal Antibody | E-AB-16729 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Ca(2+)/calmodulin-dependent protein kinase phosphatase, CaM-kinase phosphatase, CAMKP, CaMKPase, FEM 2, hFEM-2, KIAA0015, Partner of PIX 2, POPX2, PP2C phosphatase, Ppm1f, PPM1F, Protein fem-2 homolog, Protein phosphatase 1F (PP2C domain containing), Protein phosphatase 1F, Protein phosphatase Mg2+/Mn2+ dependent 1F

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell biology, Signal transduction

Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase.

Concentration: 0.8 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human PPM1F

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 50 kDa

Molecular Weight(Observed): N/A