PPP1R1A Polyclonal Antibody | E-AB-18912

PPP1R1A Polyclonal Antibody | E-AB-18912 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: I 1, I-1, I1, Inhibitor 1, IPP 1, IPP-1, IPP1, Ppp1r1a, PPR1A, Protein phosphatase 1 regulatory (inhibitor) subunit 1A, Protein phosphatase 1 regulatory subunit 1A, Protein phosphatase inhibitor 1

Application: IHC, ELISA

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal transduction

Background: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.

Concentration: 1.02 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human PPP1R1A

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A