PPP3CC Antibody| F40087-0.08ML/F40087-0.4ML

PPP3CC Antibody| F40087-0.08ML/F40087-0.4ML | Gentaur UK, US & Europe Distribution

Background: Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:50-1:100

Application Note: Titration of the PPP3CC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This PPP3CC antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 18-47 from the human protein was used as the immunogen for this PPP3CC antibody.

Storage: Aliquot the PPP3CC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A