PRDM10 polyclonal Antibody | BS60764

PRDM10 polyclonal Antibody | BS60764 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The PR-domain containing proteins (PRDMs) have a common involvement in the modulation of gene activities. A PR-domain family member usually produces two products, which differ by the presence or absence of the PR domain. The PR-plus product is underexpressed or disrupted, whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, which is a result of either genetic or epigenetic events, appears to be a determining cause of malignancy. PRDM10 (PR domain containing 10), also known as PFM7 or TRIS, is a 1,147 amino acid protein that contains ten C2H2-type zinc fingers and one SET domain. Existing as six alternatively spliced isoforms, PRDM10 localizes nucleus and may be involved in transcriptional regulation. PRDM10 may also play a role in the development of the central nerve system, as well as in the pathogenesis of neuronal storage disease.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PRDM10 polyclonal Antibody detects endogenous levels of PRDM10 protein.

Molecular Weight: ~ 130 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PR domain zinc finger protein 10; PR domain-containing protein 10; Tristanin; PRDM10; KIAA1231; PFM7; TRIS

Immunogen: A synthetic peptide corresponding to residues in Human PRDM10

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: