PRDX3 Polyclonal Antibody | E-AB-40188

PRDX3 Polyclonal Antibody | E-AB-40188 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Antioxidant protein 1, AOP 1, AOP-1, AOP1, HBC189, MER5, MGC104387, MGC24293, mitochondrial, peroxiredoxin 3, Peroxiredoxin III, Peroxiredoxin-3, PRDX3, PRDX3, PRO1748, Protein MER5 homolog, PRX III, Prx-III, PRX3, SP 22, SP-22, SP22, Thioredoxin dependent peroxide reductase mitochondrial, Thioredoxin-dependent peroxide reductase

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Background: This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human Thioredoxin-dependent peroxide reductase, mitochondrial protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 28 kDa

Molecular Weight(Observed): 28 kDa