PRKCE (PKC epsilon ) monoclonal Antibody | MB64632

PRKCE (PKC epsilon ) monoclonal Antibody | MB64632 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: FC, WB

Application Range: WB 1:2000, FLOW 1:100

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS) -mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: protein kinase C epsilon

Molecular Weight: 83.5 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: nPKC-epsilon; PKCE

Immunogen: Full length human recombinant protein of human PRKCE (NP_005391) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A