Prostatic Acid Phosphatase, Human Semen | P1445

Human Prostate Acid Phosphatase is also known as human prostatic acid phosphatase (PAP, ACP) is an alternative marker to Prostate Specific Antigen (PSA) for prostate malignancy. Prostatic Acid phosphatase (PAP) is a phosphatase, a type of enzyme, used to free attached phosphate groups from other molecules during digestion. Acid Phosphatase is stored in lysosomes and functions when these fuse with endosomes, which are acidified while they function; therefore, Human Acid Phosphatase has an acid pH optimum below 7.0.

P1445 | Prostatic Acid Phosphatase, Human Semen DataSheet

Biomolecule/Target :

Synonyms: ACP, PAP, Acid Phos, 5'-nucleotidase, 5'-NT, Ecto-5'-nucleotidase, Thiamine monophosphatase, TMPase, PAPf39

Alternates names: ACP, PAP, Acid Phos, 5'-nucleotidase, 5'-NT, Ecto-5'-nucleotidase, Thiamine monophosphatase, TMPase, PAPf39

Taglines: Marker for the progression of prostate cancer

NCBI Gene ID #: 55

NCBI Gene Symbol: ACPP

Gene Source: Human

Accession #: P15309

Recombinant: False

Source: Human Semen

Purity by SDS-PAGE: >98%

Assay: SDS-PAGE.

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity: > 100 U/mg (Dimension® Clinical Chemistry System)

Results:

Binding Capacity:

Unit Definition: One unit will catalyze the hydrolysis of one micromole of thymolphthalein monophosphate to thymolphthalein and phosphate per minute at pH 5.6 and 37°C.

Molecular Weight: ~100,000

Concentration:

Appearance: Lyophilized powder

Physical form description: Lyophilized

Reconstitution Instructions: Reconstitute in water to the concentration of 10 mg/mL

Amino acid sequence:

Handling: Centrifuge the vial prior to opening.

Usage: