PRRG2 Antibody | 15-514

PRRG2 Antibody | 15-514 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human PRRG2 (NP_001303264.1) .

Research Area: Cell Cycle

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: Mouse liver

Positive Control 2: Mouse lung

Positive Control 3: Rat liver

Positive Control 4: Rat lung

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 23kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: PRGP2, transmembrane gamma-carboxyglutamic acid protein 2, proline rich Gla (G-carboxyglutamic acid) 2, proline-rich Gla (G-carboxglutamic acid) polypeptide 2, proline-rich Gla (G-carboxyglutamic acid) polypeptide 2, proline-rich Gla protein 2, proline-rich gamma-carboxyglutamic acid protein 2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.