PRT-060318 | B1911

PR-060318 is a potent and selective Syk inhibtor. It prevents both HIT (Heparin-induced thrombocytopenia) immune complex-induced thrombocytopenia and thrombosis in vivo.

PR-060318 is a potent and selective Syk inhibtor. It prevents both HIT (Heparin-induced thrombocytopenia) immune complex-induced thrombocytopenia and thrombosis in vivo.

B1911 | PRT-060318 DataSheet

Alternate Name/Synonyms: 2-(((1R,2S)-2-aminocyclohexyl)amino)-4-(m-tolylamino)pyrimidine-5-carboxamide; PRT318

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1194961-19-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₂₄N₆O

Molecular Weight: 340.42

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective Syk inhibtor

MDL Number: N/A

PubChem CID: 11493841

SMILES: CC1=CC(=CC=C1)NC2=NC(=NC=C2C(=O)N)NC3CCCCC3N

InChi: InChI=1S/C18H24N6O/c1-11-5-4-6-12(9-11)22-17-13(16(20)25)10-21-18(24-17)23-1

InChi Key: NZNTWOVDIXCHHS-LSDHHAIUSA-N