PSAT1 polyclonal Antibody | BS8371

PSAT1 polyclonal Antibody | BS8371 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IF

Application Range: WB: 1:500~1:2000 IF: 1:50~1:200

Background: PSAT1 (phosphoserine aminotransferase 1), also known as phosphoserine aminotransferase, phosphohydroxythreonine aminotransferase, endometrial progesterone-induced protein, PSA, PSAT, EPIP or MGC1460, is a 370 amino acid protein belonging to the class-V pyridoxal-phosphate-dependent aminotransferase family and serC subfamily. PSAT1 catalyzes the second step in the L-serine synthesis pathway, converting 3-phosphohydroxypyruvate into 3-phosphoserine. While highly expressed in pancreas, brain, kidney and liver, PSAT1 is expressed at very low levels in colon, testis, thymus and prostate. There are two known isoforms of PSAT1 which result from alternative splicing events, and the gene encoding PSAT1 maps to human chromsome 9q21.2. PSAT1 deficiency can cause phosphoserine aminotransferase deficiency (PSATD), whose symptoms include psychomotor retardation, intractable seizures, acquired microcephaly and hypertonia.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PSAT1 polyclonal Antibody detects endogenous levels of PSAT1 protein.

Molecular Weight: ~ 40 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; PSAT1; PSA

Immunogen: Recombinant full length Human PSAT1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: