PTGFR Antibody (Center) [APR13020G]

PTGFR Antibody (Center) [APR13020G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PTGFR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 169-199 amino acids from the Central region of human PTGFR.

Cellular Localisation: Cell membrane; Multi-pass membrane protein.

Molecular Weight: 40055

Clone: Polyclonal

Gene Name: PTGFR

Gene ID: 5737

Function: Receptor for prostaglandin F2-alpha (PGF2-alpha) . The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity) . Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.

Summary: Tissue Location: Eye..

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Prostaglandin F2-alpha receptor, PGF receptor, PGF2-alpha receptor, Prostanoid FP receptor, PTGFR